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Nils Willison (1880-1964) was a Lutheran pastor, professor and administrator. Willison graduated from the University of Toronto in 1908, received a BA from Queens University, and was the first graduate of Evangelical Lutheran Seminary (now Waterloo Lutheran Seminary) in 1914. He was a professor at Waterloo College from 1918-1928, and also served as Registrar. From 1928-1936 Nils Willison was pastor of Trinity Lutheran Church, Hamilton. He was President and Dean of the Lutheran College and Seminary in Saskatoon, Saskatchewan, from 1936-1949. Willison returned to Ontario in 1949 and served as pastor of the Owen Sound-Wiarton parish until 1952. He was a member of the Board of Governors of Waterloo College and Seminary for 12 years. The University of Western Ontario granted Nils Willison an honorary Doctor of Divinity degree in 1944. Wilfrid Laurier University’s Willison Hall is named in his honour.

John Theberge (1940- ) was a professor and researcher in the Faculty of Environmental Studies, University of Waterloo, from 1972 until his retirement in 2000. Theberge received his BSc from the University of Guelph, MSc from the University of Toronto, and PhD from the University of British Columbia. John Theberge's career focused on his wolf research, pioneering a technique using vocal patterns to identify wolves. John Theberge and his co-researcher and wife Mary Theberge became Canada's premier timber wolf research team, receiving international recognition for their field research. In 1993, Equinox magazine proclaimed John and Mary Theberge "Environmentalist of the Year". In 1998 they were presented with the Harkin Medal from Canadian Parks and Wilderness Services.

Ann Augusta Stowe-Gullen (1857-1943) was a medical doctor, a lecturer and a suffragette. She was born in Mt. Pleasant, Ontario, the daughter of John Stowe and Emily Howard Jennings. She married John Benjamin Gullen in 1883. She died in Toronto. Stowe-Gullen was educated at the Toronto School of Medicine, then at the Faculty of Medicine at Victoria University, Toronto, where she became an M.D. in 1883, the first woman to graduate from a Canadian medical school. Immediately after graduating she was appointed Demonstrator in Anatomy at the Woman’s Medical College in Toronto (from 1894 onwards known as the Ontario Medical College for Women). In 1890 she was appointed Lecturer on Diseases of Children, subsequently Professor of Diseases of Children. She also served among the original staff members of Toronto Western Hospital (founded in 1896). Stowe-Gullen was a member of the Ontario College of Physicians and Surgeons, the Ontario Social Service Council, the Senate of the University of Toronto where she represented women in the medical profession (1912-24), the Toronto Board of Education (1892-96), the University Women's Club, the Women's Art Association, the Women's Board at Toronto Western Hospital, and the Women's Canadian Club. She was also active in the suffrage, temperance and other social movements. She was among the founders of the National Council of Women in 1893, (President) of the Canadian Suffrage Association, (Vice-President) of the National Council of Women, and she succeeded her mother as President of the Dominion Women’s Enfranchisement Association in 1903. In 1935 she was awarded the Order of the British Empire.

Emily Howard Jennings Stowe (1831-1903) was a teacher and principal, a medical doctor, and a suffragette. Educated at home, Stowe became a teacher in 1846 and graduated from the Provincial Normal School in Toronto, Canada West in 1854. In 1865 Stowe applied to study medicine at the University of Toronto, but was denied entry because she was a woman. Unable to pursue her education in Canada, she attended the New York Medical College for Women. After graduating in 1867, Stowe returned to Toronto to practice medicine without a license. In 1870 she was allowed to attend the University of Toronto and was granted a medical license in 1880. In 1877 Emily Stowe organized Canada's first suffrage organization, initially called the Toronto Women's Literary Club, which later became the Toronto Women's Suffrage Club.

Jim Stapleton was a student at Waterloo Lutheran University (now Wilfrid Laurier University) from 1961 to 1965.

John Frederick Nathanael Spady (1879-1947) was a musician and composer in Waterloo, Ontario. Taught by his mother, who was the organist at St. John’s Lutheran Church in Waterloo for more than 30 years, Spady excelled as a pianist and violinist. He authored more than 600 pieces of music.

Harold Russell was a student at Waterloo College from 1954 to 1958. He was a member of the Waterloo College Detachment of the University of Western Ontario Contingent of the Canadian Officers' Training Corps.

Henry A. Regier (1930 - ) was a professor of zoology and environmental studies at the University of Toronto until his retirement in 1995. Regier received his BA from Queen's University, a professional teaching certificate from the University of Toronto, and his PhD from Cornell University. In 1966 he joined the University of Toronto. Henry Regier's research interests include the Great Lakes, human use of aquatic systems, world population, and climate change. Regier served as a Canadian commissioner on the Great Lakes Fishery Commission, from 1980 to 1989. From 1987 to 1990 he served on the Great Lakes Science Advisory Board of the International Joint Commission of Canada and the USA. Regier has received many awards, including the Conservation Award of the Federation of Ontario Naturalists in 1980, the Centenary Medal by the Royal Society of Canada in 1986, the Award of Excellence of the American Fisheries Society in 1992, and the Lifetime Achievement Award from the International Association of Great Lakes Research in 2005.